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07th June 2024

How Much Weight Can You Lose With Wegovy?

Dr. Jill Barat, PharmD
How Much Weight Can You Lose With Wegovy?

Wegovy is a weight loss medication that is getting a lot of chatter online for its ability to help people slim down. But, just how much weight are people losing from using Wegovy?

In this article, we will review the clinical trials to see just how much weight loss the studies showed on average and in what time period.


How much weight did people lose with Wegovy in the clinical trials?

According to the Wegovy clinical trials, some people lost approximately 15% of their body weight after using Wegovy long-term. One study reported an average decrease of 15.8% in body weight across 388 participants.


How long did it take people to lose weight on Wegovy in the studies?

When looking at the impressive statistic above of people losing about 15% of their body weight, that might seem pretty great. But, it is also important to keep in mind the time frame for weight loss when using Wegovy.

The studies mentioned above reported this average of 15.8% of body weight lost, only after 68 weeks of consistent weekly Wegovy injections. So, if approximately 15% of your body weight lost is what you are aiming for, it may take over a year for that to happen. If this is your goal, mentally and financially prepare yourself for a long-term treatment. Of course, this is only an average, so some people may experience different weight loss percentages, and in different time frames.


What is a reasonable weight loss expectation with Wegovy

If you are planning on sticking to your Wegovy regimen 100%, as well as abiding by diet and exercise recommendations, you might expect to lose up to approximately 15% of your body weight after at least a year of treatment.

One study found that after 6 months, in people who also underwent 14 counseling sessions regarding diet and exercise, participants shed between 5 to 10% of their body weight. This suggests that really understanding and implementing healthy diet and lifestyle habits may deliver weight loss results even faster. 


Who might not lose weight as expected when using Wegovy

Even though the studies and advertisements constantly point to the “15% of your body weight lost” statistic, this may not be the case for everyone. While Wegovy can be a good tool for weight loss while reducing your appetite and making you feel fuller faster, there are still factors that may hinder weight loss.

Firstly, it has been found that people who have diabetes may not lose weight as quickly or reliably on Wegovy as people who are overweight or obese but not diabetic. The Wegovy package insert states that 25.1% of people with type 2 diabetes and obesity or overweight lost 15% or more of their body weight. While 47.9% of people that had obesity and overweight, but did not have type 2 diabetes lost 15% or more of their body weight. So, having type 2 diabetes might make it harder to hit that 15% of body weight lost goal.

Also, studies have shown that Wegovy users lost more weight when they also implemented a healthy diet and exercise in addition to the medication. So, if someone was using Wegovy, but did not change their eating habits or activity levels at all, they may not lose weight as expected when using Wegovy.


PeptideVite from Zen Nutrients for digestion support while using GLP-1 medications

Some people may not lose the weight they expected when using Wegovy, simply because the side effects were bad enough that they could not continue on the treatment. Since this is a treatment that needs a significant amount of time to help you lose the maximum amount of weight – cutting your treatment short due to side effects may mean you don’t hit your goals. The most common side effects of Wegovy are gastrointestinal-related, including nausea, stomach upset, diarrhea, and constipation.

To help support your GLP-1 treatment, you can consider supplements that might help support healthy metabolism levels and comfortable digestion.* PeptideVite from Zen Nutrients is a pharmacist and physician-developed supplement with vitamins, minerals, and herbal extracts to possibly make your GLP-1 journey a more comfortable and successful one.*




*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.