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28th July 2023

How Does Ozempic (Semaglutide) Work for Weight Loss?

Dr. Devan Patel, PharmD
How Does Ozempic (Semaglutide) Work for Weight Loss?

Weight loss isn’t easy for everyone, but it is an important aspect of maintaining a healthy lifestyle if you are overweight. Many people try different diets and exercises, but still find it difficult to shed those extra pounds. 

However, a new drug on the market is helping people lose a significant amount of weight – Ozempic. Ozempic is prescribed to diabetics to help them manage their blood sugar, but it has surprising weight loss benefits.

But, just how does Ozempic work for weight loss?

Below, we'll explore how Ozempic works for weight loss and how it can help you achieve your weight loss goals.


How Does Ozempic Work for Weight Loss?

Ozempic is a medication originally intended to treat diabetes. It contains semaglutide, which is a GLP-1 receptor agonist that mimics the gut hormone, GLP-1. Semaglutide works by increasing insulin production and suppressing glucagon secretion, which reduces blood sugar levels. 

However, this drug also delays gastric emptying and affects the appetite centers of the brain, causing people to eat less and feel fuller for longer periods of time. In turn, people eat fewer calories, which can result in weight loss. 

The weight loss benefits of Ozempic were discovered by accident during clinical trials for its diabetes treatment. This led to a stronger version of the medication (Wegovy) eventually being approved by the FDA for specific use as a weight loss drug. 

Studies have shown that Ozempic can help people lose an average of 12-15 pounds over a 10-month period. Additionally, Ozempic can lower the risk of heart attack and stroke in people with diabetes. 

Do You Have To Exercise While Taking Ozempic for Weight Loss?

There are no specific guidelines for how much you should exercise or what you should eat while taking Ozempic for weight loss. So, how does Ozempic work for weight loss without dieting and exercising? 

While eating a certain diet and exercising are not necessary to take the medication, it is highly recommended that you do. Ozempic can help you eat fewer calories, which will help you shed some pounds over time. However, including regular exercise and avoiding high-calorie foods will maximize your weight loss potential.

Sticking to lower-calorie foods will reduce your calorie intake further and exercising will increase the number of calories you burn daily. Both factors can help speed up your weight loss efforts and result in a larger amount of weight loss. 

Remember, Ozempic isn’t a miracle drug that magically makes fat disappear. It works with your body’s natural hormones to lower your blood sugar levels and make you feel less hungry. However, intentionally overeating will negate these weight loss benefits. 


How Is Ozempic Administered?

Ozempic is administered at home via injection once a week from a pre-filled pen. The dosage is gradually increased over several weeks to reach the maximum dose of 1 mg. 

The injection is typically given in the abdomen, thigh, or upper arm. People who are taking Ozempic for type 2 diabetes should continue to take it as prescribed by their doctor even if they are using it for weight loss.


Are There Any Side Effects of Ozempic?

It's important to note that like any medication, Ozempic can have side effects. Some common side effects include nausea, vomiting, and diarrhea. Side effects should go away after a few days or a few weeks. 

You can reduce your risk and severity of these side effects by practicing lifestyle habits like eating slower, eating smaller portions, and avoiding foods that irritate your stomach (like greasy or fatty foods). 

Additionally, taking certain dietary supplements like PeptideVite may be useful. PeptideVite is a multi-nutrient supplement with ingredients studied for their possible benefits in reducing symptoms like stomach upset, nausea, and bloating.* It can be taken alongside Ozempic treatment and is used by many to make taking the medication more tolerable.*

More serious side effects of Ozempic can include kidney problems and pancreatitis, but these side effects are rare. However, always talk to your doctor about any existing medical conditions before taking Ozempic. 


How Does Ozempic Work for Weight Loss? The Bottom Line

Overall, Ozempic can be a helpful tool for men and women who are struggling with weight loss. It works by reducing appetite and increasing feelings of fullness, which leads to less calorie consumption and eventual weight loss. 

However, it's important to remember that weight loss medications should always be used in combination with a healthy diet and exercise plan. Ozempic is not a miracle weight loss cure. 

To find out if Ozempic is right for you, talk to your doctor. Be sure to provide them with any relevant medical history, questions, or concerns. Weight loss is difficult but fortunately, Ozempic may be able to help. 



*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.