Free Shipping over $40.

25th August 2023

Can Semaglutide Work for Weight Loss in Non-Diabetics?

Dr. Devan Patel, PharmD
Can Semaglutide Work for Weight Loss in Non-Diabetics?

Weight loss can be difficult, even with diet and exercise. CDC statistics show that about 42% of Americans are obese while 30% are overweight

Obesity is linked to numerous health conditions including potential life-threatening consequences like heart attacks and high blood pressure. Losing weight and maintaining a healthy BMI is the best defense for most people against potentially life-threatening health conditions. 

Fortunately, a new medication known as Semaglutide is making the weight loss process easier for many people. Semaglutide was initially created to treat type 2 diabetes, but recent studies have indicated that it can be used for weight loss in non-diabetics. 

Keep reading to learn more about Semaglutide for weight loss in non-diabetics and how it might benefit you.


What Is Semaglutide? 

Semaglutide is a medication that belongs to the glucagon-like peptide-1 (GLP-1) class of drugs. It works by stimulating insulin production, suppressing appetite, and slowing down digestion. 

Semaglutide has been approved by the FDA as a treatment for type 2 diabetes since 2017 and is most commonly sold under the brand name, Ozempic. Weight loss is a common side effect and benefit of taking Semaglutide with most people able to lose up to 15% of their body weight after one year on the highest dosage.

The successful weight loss benefits of Semaglutide sparked research into Semaglutide for weight loss in non diabetics. Semaglutide would sometimes be prescribed to non-diabetics off-label for weight loss. 

Recently, however, Semaglutide has been approved for weight loss in non-diabetics under the brand name Wegovy.  


Semaglutide for Weight Loss in Non Diabetics: How Does It Work? 

Semaglutide mimics hormones in your body that release insulin. It helps control your blood sugar levels both after eating and in a fasting state. 

Semaglutide also helps to delay gastric emptying and suppress appetite, meaning you’ll feel full longer. The less hungry you are, the less likely you are to overeat, which contributes to obesity. 

By helping you reduce your overall calorie intake, Semaglutide can help you lose weight over time. 


What Are the Side Effects of Using Semaglutide?

Like most medications, Semaglutide can have side effects. The most common side effects of Semaglutide include gastrointestinal (GI) symptoms such as nausea, vomiting, diarrhea, and constipation. 

These side effects usually occur during the first week of treatment and then subside. In rare cases, there is also a risk of pancreatitis and thyroid tumors. 

Though Semaglutide is considered safe for most people, remember that any medication should only be taken under the advice and guidance of a medical professional.


How Can You Reduce Semaglutide Side Effects?

Though side effects of Semaglutide generally dissipate after a few days to a few weeks, they can be an uncomfortable experience. If you are having trouble coping with Semaglutide side effects like nausea and constipation, there are some things you can do to reduce their severity. 


Eat Smaller, More Frequent Meals

Semaglutide delays gastric emptying, meaning the more food you eat, the longer it will stay in your stomach. This can cause constipation, acid reflux, nausea, and overall discomfort.

Eating smaller, but more frequent meals helps you digest your food more easily while still getting enough daily nutrition. 


Move More

Exercise aids digestion by helping food move through your digestive tract more easily. To reduce symptoms like constipation and acid reflux, avoid lying down after meals and instead go for a walk. 

However, refrain from doing intense exercise immediately after eating as this may worsen GI symptoms. 

Avoid Certain Foods

Avoid foods and beverages like greasy fried foods and alcohol. These foods irritate the GI tract and can make GI side effects worse. 

Alcohol can also cause a drop in blood sugar, which can interact negatively with Semaglutide. 


Consider Supplements

PeptideVite is a dietary supplement formulated specifically for supporting GLP-1 medications like Semaglutide. 

It contains natural ingredients like vitamins, minerals, and herbs that have been backed by scientific research for their potential effectiveness in reducing GI symptoms and boosting metabolism.*

PeptideVite may help reduce certain symptoms of Semaglutide, making your overall experience with the medication more tolerable.*


Who Is Eligible To Use Semaglutide for Weight Loss?

Currently, Semaglutide for weight loss in non-diabetics is only FDA-approved for individuals who have a BMI (Body Mass Index) of 27 or higher and who have at least one weight-related condition such as hypertension or type 2 diabetes. 

However, your doctor can prescribe Semaglutide off-label if they believe it could benefit your weight loss journey.

The Takeaway

Semaglutide has proven to be an effective medication for weight loss in non-diabetics. It works by suppressing appetite, stimulating insulin production, and slowing down digestion. 

If you’re struggling with weight loss, Semaglutide could be a safe tool to help you shed more weight and reach your health goals. 



*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.