Does Zepbound Need To Be Refrigerated?

Zepbound is a popular injectable medication to help people lose weight.

Since this medication has become so popular, it's possible that this may be the first time some people are using an injectable medication at all. For first-timers, this can come along with many questions as far as storage and the appropriate temperature to keep your medication in.

Below, we consult the Zepbound package insert to give you the exact details on storage for your Zepbound medication. We will cover if it needs to be refrigerated, and if room temperature or freezing temperatures are also ok.

If you are ever unsure if your medication was stored appropriately, or if it is safe to use, it’s best to contact your doctor or pharmacist first before using.

Does Zepbound need to be refrigerated?

According to the package insert the recommended storage temperature for  Zepbound is in the refrigerator. This means temperatures ranging from 2°C to 8°C (Or 36°F to 46°F). 

So, if you have the capability to store your Zepbound in the fridge, this is the best choice for the sterility and stability of the medication.

However, the package insert does list some acceptable room temperature storage conditions as well. We will explain these in more detail below. But, remember, if you’re going for the ideal storage, the fridge is the winner here.

How long can Zepbound be stored at room temperature?

If refrigerator storage is not an option, the package insert does give some parameters where room temperature storage for your Zepbound will be ok.

You can store your single-dose Zepbound medication at room temperature for up to 21 days. This means a temperature below 30°C (86°F).

However, once that 21-day threshold has been reached, you will need to discard the medication, even if it still contains medication, or if the expiration date printed on the label has not yet occurred. This is for your safety and the efficacy of the medication.

Even if the medication was stored in the fridge for a certain amount of time, and then moved to room temperature, it still needs to be discarded after it has been at room temperature for 21 days.

Can you store Zepbound in the fridge again after storing it at room temperature?

If your Zepbound medication was stored at room temperature for some period of time, and you now want to move it back to the fridge to “extend the dating”, this is not recommended.

The package insert states that once the Zepbound has been stored at room temperature, you should not now store it in the fridge. In this case, this medication will need to be discarded after 21 days since it was first left at room temperature.

Can you freeze Zepbound?

You should not freeze your Zepbound medication at all. If you have a Zepbound medication that is currently or previously frozen, you should not use it and discard the medication.

Other Zepbound storage requirements

Another note of storage of your Zepbound medication is the container and light amount in the environment where it is kept.

It is recommended to keep your Zepbound medication in its original container in order to help protect it from light. 

Does Zepbound need to be refrigerated?: Bottom Line

It is recommended to store your Zepbound in the refrigerator at all times.

However, if this is not an option, you can store your medication at room temperature for a short amount of time. Zepbound can be stored at room temperature for 21 days. After 21 days, you will need to discard the medication if it is stored at room temperature. This applies even if the printed expiration date is longer.

Never store Zepbound in the freezer, and don’t use Zepbound if it was frozen previously.

Store your medication in its original container out of reach of pets and children.

PeptideVite from Zen Nutrients as a digestion aid*

PeptideVite is a comprehensive supplement developed by pharmacists and doctors at Zen Nutrients.

The ingredients inside PeptideVite were specifically chosen to help with comfortable digestion in people who are using GLP-1 inhibitor medications like Wegovy or Zepbound.* Since these medications often come along with gastrointestinal side effects, giving people a way to make their treatment more comfortable was the ultimate goal. For some people, PeptideVite may make side effects more manageable and allow them to continue their weight loss treatments for longer.*

Learn more about PeptideVite from Zen Nutrients today.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.