Best 5 Vitamins and Supplements for Liver Health

If you are looking into a supplement to help support your liver health, you have likely come across a lot of combination products. Many of these products contain a blend of vitamins and herbal extracts that may have benefits in terms of liver health support.

But, just which of these liver supplements is the best if you are looking to purchase only one? 

In this roundup, we will go over some of the pros and cons of a few of the most popular liver health vitamins and supplements. We will wrap up by sharing the one we think is the best all around.

What does the liver do in your body?

The liver performs many functions to help you stay healthy and feel your best. A functioning liver is necessary for life, and you only have one of them, so it’s critical to help protect it and keep it healthy.

Some of the responsibilities of your liver include:

• Metabolism regulation

• Healthy digestion

• Naturally detoxing your body

• Clearing waste and breaking down chemicals and medications

• Storing extra glucose for release when blood sugar is low

• Healthy blood circulation

What sorts of things can harm or negatively affect your liver?

• Eating processed foods

• Eating fried or high-cholesterol foods

• Eating sugary foods

• Overeating

• Lack of exercise/sedentary lifestyle

• Low metabolism

• Being overweight or obese

• Alcohol consumption

• Certain medications

Many of the things on this list are things that many of us occasionally indulge in, or need to do, like taking certain medications. But, when these happen often or all at once, it can be taxing on the liver. 

Making healthy lifestyle adjustments like minimizing alcohol use, getting plenty of movement in, and consuming a healthy well-rounded diet with a focus on lean protein, fiber, and fruits and vegetables.

How might a liver supplement help you?

• General liver health support

• Healthy digestion support

• Healthy energy levels

• Mental health and focus support

In addition to trying to make the lifestyle changes suggested above, some people also include a liver support supplement. Many of these liver supplements utilize plant-based extracts that may help support overall liver health and normal functioning. 

If you want to give one of these a try to see how you feel, it is recommended to use them for at least a few months to give them a chance to work.

1. The Everyday Liver Vitamin (TELV) by Zen Nutrients 

Overall Grade: A+

Pros:

• 15 ingredients

• Organic ingredients

• Features patented high-bioavailability ingredients

• Ingredients clinically studied for liver health

• Money-back guarantee

• Vegetarian and vegan friendly

• Made in the U.S. and non-GMO

Cons:

• May seem costly to some (although discounts available)

The Bottom Line:

The Everyday Liver Vitamin from Zen Nutrients is a solid blend of 15 ingredients meant to support general liver health and wellness. The top ingredients here are bergamot, artichoke, milk thistle extract, and turmeric with Bioperine to enhance absorption.

A proprietary blend is included that combines ginger, dandelion, and CoQ10 – just to name a few. The bergamot extract is a patented formulation called BergaCynFF. BergaCynFF is meant to be a more bioavailable form of bergamot to help it get into your system more easily.

We also like that many of the ingredients are organic, when possible, and that the supplement itself was developed by pharmacists and doctors.

There is a money-back guarantee, and the ingredients are vegetarian and vegan-friendly.

The price comes in at $39.99 for a bottle of 60 capsules (a 30-day supply), so this may seem pricey for some. Although given the quality and quantity of ingredients, it’s not too extravagant at $1.33 per day. If price is an issue for you, consider signing up for a subscription to save 5%, or check the Zen Nutrients website for occasional sales and discount codes.

2. DOSE liver support supplement shot

Overall Grade: B

Pros:

• Drinkable (good for those who don’t like swallowing pills)

• Clinically studied ingredients

• Organic ingredients

• Vegetarian and vegan friendly

Cons:

• Only 4 ingredients

• Very expensive

• No money-back guarantee

The Bottom Line:

DOSE is a liver support supplement shot that may be a favorite for people who are not fans of swallowing capsules or tablets. This drinkable supplement contains 4 ingredients: turmeric extract, milk thistle extract, ginger powder, and dandelion powder. All of which have pretty solid studies behind their benefits for liver health and support. These ingredients are also organic, which is a plus. DOSE is vegan, sugar-free, gluten-free, and non-GMO, keeping things open for a wide range of people with dietary restrictions.

You are meant to use one drinkable shot per week, for an easy-peasy dosing schedule. But, depending on if you get a 3 pack or a 6 pack, that may cost you $31 or $28.33 per 2oz “shot”. This does come off as a bit pricey, but may be worth it for some people to have a once-weekly liver supplement that isn’t a capsule you need to swallow daily. There is also no money-back guarantee for DOSE products.

3. Liver Health Formula by Pure Health Research

Overall Grade: B+

Pros:

• 9 ingredients

• Vegetarian and vegan friendly

• Money-back guarantee

• Affordable price point

• Money-back guarantee

Cons:

• No organic ingredients

• No patented high-bioavailability ingredients

• Not clinically studied

The Bottom Line:

Liver Health Formula by Pure Health Research contains 9 supplement ingredients blended together. By weight, the top ingredients are turmeric, beetroot extract, L-glycine, and dandelion root powder. There is also a little Bioperine in there to enhance turmeric absorption.

This supplement was developed by naturopathic doctor, Dr. Holly Lucille, and it does have a money-back guarantee. Liver Health Formula is also vegan and non-GMO, but does not use organic ingredients.

The price point for this one is $42.90 for one 60-capsule bottle (30-day supply). But, Pure Health Research has subscribe and save offers that would reduce the cost to $26.10 for one bottle.

4. Liver MD by 1MD Nutrition

Overall Grade: C+

Pros:

• Money-back guarantee

• Made in the U.S. and non-GMO

• Use of some patented ingredients

• Relatively affordable

Cons:

• Does not use organic ingredients

• No liposomal or bioavailable technology

• May not be vegan or vegetarian friendly

• Not clinically studied

The Bottom Line:

Liver MD by 1MD Nutrition is a liver supplement formulated by a gastroenterologist aimed at focusing on liver health and how that relates to healthy digestion. It is a 7-ingredient blend, with a focus on ingredients including milk thistle, N-acetyl cysteine, alpha-lipoic acid, zinc, and selenium. Liver MD has a 90-day money-back guarantee if you don’t like it, and it’s also made in the US and non-GMO.

On the downside, Liver MD does not use organic plant ingredients, and it is unclear if this formula is suitable for vegans or vegetarians. Liver MD comes in a bottle of 60 capsules for a 30-day supply. As a one-time purchase, this runs $43 per bottle. But, if you sign up for a subscription of 6 bottles every 6 months, you can get the lowest price of $29.60 each.

5. Liverwell by Live Conscious

Overall Grade: B-

Pros:

• Use of patented ingredients

• Vegetarian and vegan friendly

• Made in the U.S. and non-GMO

• Affordable

Cons:

• 5 ingredients

• No use of organic ingredients

• No liposomal or bioavailable technology

• No money back guarantee

The Bottom Line:

Liverwell by Live Conscious is a 5 ingredient blend meant to support liver health. The ingredient focus here is on N-acetyl cysteine, selenium, alpha-lipoic acid, milk thistle fruit extract, and zinc. They utilize a patented form of milk thistle extract called Siliphos. Liverwell is listed as being vegan and vegetarian friendly, it’s made in the US, and does not use GMO ingredients.

The cons to Liverwell may be the lack of using organic plant ingredients where possible, and no money-back guarantee if it does not work out for you. The pricing is affordable at $25 per 60 count bottle (30-day supply). To get a cost savings, you could also opt for a subscription program of 6 bottles shipped to you at a time. This could take the price as low as $18.40 each.

Our vote for top liver health supplement: The Everyday Liver Vitamin

While many supplements on this list have many “pros” for a solid liver health supplement. Our vote for the best all-around liver supplement goes to The Everyday Liver Vitamin by Zen Nutrients. It combines the most liver-supportive ingredients, with a focus on organic plant ingredients, and choosing the more bioavailable forms of each. They have confidence in their product with a money-back guarantee, and they manufacture in the US without GMO ingredients. This is a formula that works for omnivores, vegetarians, and vegans alike. With a moderate, but affordable price tag, this is the liver supplement that ticks the most boxes for a well-rounded choice.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.